Pentorse 100 Inj.
Pentorse 100 is an injectable veterinary medication primarily used to treat non-infectious inflammatory joint diseases, particularly osteoarthritis, in dogs. It contains Pentosan Polysulfate Sodium (PPS), a semi-synthetic polysaccharide derived from beechwood.
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Description
Uses and benefits
Treats Osteoarthritis & Traumatic Joint Disease: Pentorse 100 is effective in managing conditions like osteoarthritis, osteochondrosis, and degenerative joint diseases.
Reduces Inflammation and Pain: It possesses anti-inflammatory properties that help alleviate joint pain and inflammation.
Chondroprotective Action: Pentorse 100 protects cartilage, inhibits the loss of proteoglycans, and promotes the regeneration of damaged joint tissue, thereby slowing the progression of osteoarthritis.
Improves Joint Lubrication: It stimulates the production of hyaluronic acid, increasing the formation of synovial fluid which helps lubricate the joints and enhance mobility.
Inhibits Destructive Enzymes: Pentorse 100 works by inhibiting enzymes that break down cartilage.
Potential for Long-Term Effects: It may offer longer-lasting effects compared to other treatment options.
Dosage
Determining the appropriate dosage of Pentorse 100 for dogs requires the guidance of a veterinarian. The medication is typically administered via subcutaneous injection. A common treatment protocol involves a series of injections given over a specific period, often with a rest period before repeating the course. The total number of courses administered within a year is usually limited. It is crucial that Pentorse 100 is used strictly under the guidance of a veterinarian to ensure proper administration and monitoring.
Possible Side Effects
While generally considered safe, some animals may experience mild side effects, such as:
Temporary discomfort or pain at the injection site
Mild gastrointestinal upset, including vomiting or diarrhea
Serious side effects are rare, but in some cases, Pentosan Polysulfate Sodium has an anticoagulant effect, which may increase the risk of unusual bruising, bleeding (including nosebleeds and heavy gum bleeding), blood in vomit or stool, or black and tarry stools.
Contraindications
Pentorse 100 should not be used in dogs with:
Advanced liver or kidney impairment
Blood disorders, coagulation disorders, bleeding, or malignancy (especially haemangiosarcoma)
Septic arthritis (appropriate antimicrobial therapy should be initiated in such cases)
Pregnancy or lactation
Immaturity (i.e., dogs whose long bone growth plates have not closed)
Additionally, NSAIDs, particularly aspirin, and corticosteroids should not be used in combination with Pentorse 100 due to potential interactions affecting thrombocyte adhesion or counteracting the drug’s action.
Important Notes
Always consult with a veterinarian for proper diagnosis, dosage, and administration of Pentorse 100.
Closely monitor your pet for any adverse reactions or side effects and report them to your veterinarian immediately.
Disclaimer: This information is for general knowledge and should not be taken as medical advice. Consult with a healthcare professional before starting any new supplement regimen.
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